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RIPK1-IN-32

CAT: 0013-GTR19263827-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263827-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RIPK1-IN-32 is an RIPK inhibitor with anti-inflammatory properties. It inhibits nitric oxide (NO) release, with an IC50 of 3.26 μM. Additionally, RIPK1-IN-32 disrupts the RIPK1/NF-κB/MAPK signaling pathway, preventing nuclear translocation of p65 and c-fos, leading to reduced expression of TNF-α and IL-6 and significantly alleviating acute liver injury related to sepsis. This compound is useful for studies on acute liver injury and sepsis.
Field of Research
Cell Biology, Immunology & Inflammation, Signal Transduction
Storage Conditions
-20°C
Notes
For research use only.

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