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TRPM8 antagonist 4

CAT: 0013-GTR19263785-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263785-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TRPM8 antagonist 4 is a compound with high functional selectivity and favorable physicochemical properties, serving as a CB2R partial agonist (EC50=54.2 μM, Ki=3.2 μM) and a TRPM8 (IC50=42.3 nM) antagonist. It possesses notable anti-inflammatory and analgesic effects, demonstrating good safety by reducing the mRNA expression of TNF-α, IL-6, and IL-1β.
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery, Pharmacology & Drug Discovery; Cell Biology
Storage Conditions
-20°C
Notes
For research use only.

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