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JNK-IN-23

CAT: 0013-GTR19263454-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263454-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JNK-IN-23 (Compound K12) is an inhibitor of JNK. It effectively inhibits the proliferation of MDA-MB-231 cells with a GIC50 of 30 nM. In vivo, JNK-IN-23 blocks metastatic growth of triple-negative breast cancer (TNBC) . Additionally, it suppresses the growth of lung metastases by dual targeting of glutaminase-1 (GLS) and the pyruvate dehydrogenase complex (PDHC) .
CAS Number
1007786-48-2
Field of Research
Signal Transduction
Smiles
O=C1N=C (NC=2SC (=C (C12) C) C) C (SC=3N=C4C=CC=CC4=NC3C) C
Molecular Formula
C19H18N4OS2
Molecular Weight
382.50
Storage Conditions
-20°C
Notes
For research use only.

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