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PVTX-321

CAT: 0013-GTR19263354-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263354-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PVTX-321 is an orally active estrogen receptor α (ERα) degrader. It effectively degrades ERα with a DC50 of 0.15 nM in MCF-7 cells and also shows inhibitory activity against ERα mutants with an IC50 of 59 nM. PVTX-321 holds potential for research in ER+/HER2- breast cancer.
CAS Number
3026004-38-3
Field of Research
Metabolism Research
Smiles
C (N1CCC2 (C=3C (OC2) =C4C (=CC3) C (=O) N (C4) [C@@H]5C (=O) NC (=O) CC5) CC1) C6CC7 (C6) CCN (CC7) C8=CC (OC) =C (C=C8F) [C@H]9[C@H] (CCC=%10C9=CC=C (O) C%10) C%11=CC=CC=C%11
Molecular Formula
C51H55FN4O6
Molecular Weight
839.00
Storage Conditions
-20°C
Notes
For research use only.

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