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SHP2 ATTEC degrader-1

CAT: 0013-GTR19263336-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263336-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SHP2ATTEC degrader-1 is an ATTEC degrader targeting SHP2, achieving an 83.31% degradation rate in PANC-1 cells at 1.0 μM after 24 hours. It inhibits cell proliferation both in vitro and in vivo. SHP2ATTEC degrader-1 induces apoptosis, elevates the expression of epithelial markers (E-cadherin), and reduces the expression of mesenchymal markers (such as N-cadherin, Vimentin) .
Field of Research
Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Storage Conditions
-20°C
Notes
For research use only.

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