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EZH2-IN-23

CAT: 0013-GTR19263171-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263171-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EZH2-IN-23 (Compound 25) is an EZH2 inhibitor, exhibiting potent enzymatic inhibition against the PRC2 complex [EZH2, EED, SUZ12, AEBP2, and RbAp48] with an IC50 of 0.8 nM. It inhibits H3K27 trimethylation in cells with an IC50 of 40 nM. In rats, EZH2-IN-23 demonstrates excellent pharmacokinetic properties, achieving 100% oral bioavailability.
Field of Research
Epigenetics & Chromatin
Storage Conditions
-20°C
Notes
For research use only.

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