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SK2188

CAT: 0013-GTR19263150-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263150-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SK2188 is a potent and selective PROTAC degrader targeting AURKA (DC50 = 3.9 nM) . It induces DNA damage and apoptosis (Apoptosis), indirectly degrades MYCN, and inhibits tumor cell proliferation, offering insights for research on MYCN-amplified neuroblastoma.
CAS Number
3038446-94-2
Field of Research
Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery, Protein Biochemistry
Smiles
C ([C@@]1 (C (NCCOCCOCCOCCOC2=C3C (C (=O) N (C3=O) C4C (=O) NC (=O) CC4) =CC=C2) =O) CC[C@@H] (OC5=C (F) C (Cl) =CC=C5) CC1) C=6N=C (NC7=NC=CS7) C=CC6
Molecular Formula
C43H46ClFN6O10S
Molecular Weight
893.38
Storage Conditions
-20°C
Notes
For research use only.

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