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WRN-IN-19

CAT: 0013-GTR19263089-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263089-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
WRN-IN-19 (Compound (S) -27) is a covalent WRN helicase inhibitor, with a pIC50 of 5.4 at 0 hours and 7.5 at 4 hours in a DNA-unwinding endpoint assay. It demonstrates synthetic lethality against MSI-H (high microsatellite instability) cancer cells.
CAS Number
3058652-58-4
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology
Smiles
C (=O) (N1CC2 (C1) CCC2) [C@H]3N (C (C=C) =O) CCN (C (CC4=CC=C (C (F) (F) F) C=C4) =O) C3
Molecular Formula
C23H26F3N3O3
Molecular Weight
449.47
Storage Conditions
-20°C
Notes
For research use only.

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