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Multitarget AD inhibitor-2

CAT: 0013-GTR19262940-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19262940-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Multitarget AD inhibitor-2 (Compound VN-19) is a versatile inhibitor targeting multiple sites, acting on acetylcholinesterase (AChE, IC50 = 0.14 μM), butyrylcholinesterase (BChE, IC50 = 11.6 μM), and monoamine oxidase B (MAO B, IC50 = 0.45 μM) . It inhibits amyloid-beta protein Aβ1-42 self-induced aggregation with an inhibition rate of 47.3% at 20 μM and reduces ROS levels in SH-SY5Y cells with an inhibition rate of 80% at 25 μM. Multitarget AD inhibitor-2 can also improve cognitive decline in a scopolamine-induced Alzheimer's zebrafish model.
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Molecular Formula
C22H23NO4
Storage Conditions
-20°C
Notes
For research use only.

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