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FXIIa-IN-5

CAT: 0013-GTR19262820-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19262820-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FXIIa-IN-5 (Compound 4J) is an orally effective selective inhibitor of factor XIIa (FXIIa), with an IC50 of 21 nM. It inhibits the intrinsic coagulation pathway and demonstrates anti-inflammatory and antithrombotic activities in a Carrageenan-induced thrombosis model in mice. FXIIa-IN-5 exhibits moderate pharmacokinetic properties and mild toxicity at a dosage of 100 mg/kg.
CAS Number
3047411-80-0
Field of Research
Protein Biochemistry
Smiles
O=C (C1=CC=C (C=2C=CC=CC12) N3CCN (CCC3) C (C) C) N4N=C (N=C4N) C=5N=CC=CC5
Molecular Formula
C26H29N7O
Molecular Weight
455.55
Storage Conditions
-20°C
Notes
For research use only.

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