Products for Research Use Only

AHR antagonist 8

CAT: 0013-GTR19262711-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19262711-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AHR antagonist 8 (compound SG-02) acts as a regulator of utrophin, a dystrophin analog, and serves as an AhR antagonist with a Kd of 41.68 nM. Studies demonstrate that 800 nM of AHR antagonist 8 can upregulate utrophin by 2.7 times. Additionally, AHR antagonist 8 enhances MyHC expression, indicating its potential to promote myogenesis. ADME evaluations reveal that AHR antagonist 8 possesses some oral bioavailability.
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Molecular Formula
C16H14FN3O2S
Storage Conditions
-20°C
Notes
For research use only.