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AHR antagonist 5

CAT: 0013-GTR19207379-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19207379-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AHR antagonist 5 (Example 39) is a potent, orally bioavailable aryl hydrocarbon receptor inhibitor with an IC50 below 0.5 μM. It demonstrates significant in vivo antitumor efficacy in combination with anti-PD-1 checkpoint blockade, making it a valuable research tool for immuno-oncology studies.
CAS Number
2247953-39-3
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Smiles
Cl.Cl.Cl.CC (C) c1cnn2c (N[C@@H]3CCc4[nH]c5ccccc5c4C3) nc (nc12) -c1cncc (F) c1
Molecular Formula
C25H27Cl3FN7
Molecular Weight
550.89
Storage Conditions
-20°C
Notes
For research use only.

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