GPVI, Mouse (HEK293, His)

GPVI, Mouse (HEK293, His)

• UNSPSC Description: GPVI Protein is a platelet membrane protein with a molecular weight of ~62 kDa that is a physiological collagen receptor. GPVI is present as a complex with the homodimeric Fc receptor y-chain. GPVI must form such a dimeric complex to exhibit high affinity binding to collagen. The GPVI-induced activation mechanism is initiated by tyrosine phosphorylation of the immunoreceptor tyrosine-based activation motif (ITAM) of the FcR gamma-chain, and then this signal is transduced to many related proteins, mainly by tyrosine phosphorylation. Interaction of platelets with collagen via the receptor GPVI results in platelet activation and adhesion[1][2][3]. GPVI Protein, Mouse (HEK293, His) is the recombinant mouse-derived GPVI protein, expressed by HEK293 , with C-6*His labeled tag. The total length of GPVI Protein, Mouse (HEK293, His) is 244 a.a., with molecular weight of 40-60 kDa.
• Type: Recombinant Proteins
• Assay Protocol: https://www.medchemexpress.com/cytokines/gpvi-protein-mouse-hek-293-his.html
• Purity: 97.34
• Smiles: QSGPLPKPSL QAQPSSLVPL GQSVILRCQG PPDVDLYRLE KLKPEKYEDQ DFLFIPTMER SNAGRYRCSY QNGSHWSLPS DQLELIATGV YAKPSLSAHP SSAVPQGRDV TLKCQSPYSF DEFVLYKEGD TGPYKRPEKW YRANFPIITV TAAHSGTYRC YSFSSSSPYL WSAPSDPLVL VVTGLSATPS QVPTEESFPV TESSRRPSIL PTNKISTTEK PMNITASPEG LSPPIGFAHQ HYAK
• Molecular Weight: 40-60 kDa
• Shipping Conditions: Blue Ice
• Storage Conditions: Stored at -20°C for 2 years