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JAK1/2-IN-1

CAT: 0013-GTR19261775-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19261775-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JAK1/2-IN-1 is a potent inhibitor of JAK1 and JAK2, with IC50 values of 0.4 nM and 8.1 nM, respectively. Additionally, JAK1/2-IN-1 inhibits IL-4 and IL-13, with IC50 values of 136.5 nM and 19.1 nM, respectively (WO2023244775A1; Example 33a) .
CAS Number
3023876-01-6
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Immunology & Inflammation, Signal Transduction, Stem Cell & Developmental Biology
Smiles
C (F) (F) (F) C1=C2C (=CC (NC=3N=C (N[C@@H]4[C@@H] (C#N) CCOC4) C (C) =CN3) =C1) COB2O
Molecular Formula
C19H19BF3N5O3
Molecular Weight
433.19
Storage Conditions
-20°C
Notes
For research use only.

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