Products for Research Use Only

JAK1/2-IN-3

CAT: 0013-GTR19274198-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274198-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JAK1/2-IN-3 is an inhibitor of both JAK1 and JAK2, demonstrating IC50 values of 14.73 nM and 10.03 nM, respectively. It can induce G2/M phase cell cycle arrest and trigger endogenous apoptosis (apoptosis) by increasing Bax and caspase3/7 levels while reducing Bcl2 expression. JAK1/2-IN-3 is applicable in research related to leukemia, breast cancer, and colon cancer.
Storage Conditions
-20°C
Notes
For research use only.