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CSC-6

CAT: 0013-GTR19261746-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19261746-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CSC-6 is an inhibitor of NLRP3. It significantly reduces the secretion of IL-1β in PMATHP-1 cells, with an IC50 of 2.3 μM. CSC-6 specifically binds to NLRP3 and prevents its activation by obstructing ASC oligomerization during the NLRP3 assembly process. It effectively alleviates symptoms of sepsis and gout mediated by excessive NLRP3 activation in mouse models.
Field of Research
Immunology & Inflammation
Molecular Formula
C18H12F3NO2S2
Storage Conditions
-20°C
Notes
For research use only.

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