Products for Research Use Only

JNJ-6640

CAT: 0013-GTR19264399-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19264399-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JNJ-6640 is an inhibitor targeting Mycobacterium PurF, the first enzyme in the de novo purine biosynthesis pathway, with potent antitubercular activity. It exhibits bactericidal properties against Mycobacterium tuberculosis in vitro, with a MIC90 of 8.6 nM. By disrupting de novo purine biosynthesis, JNJ-6640 inhibits Mycobacterium tuberculosis DNA replication in vivo. Demonstrating antitubercular efficacy in acutely infected mice, JNJ-6640 is applicable for tuberculosis research.
Field of Research
Infectious Disease & Virology
Storage Conditions
-20°C
Notes
For research use only.

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