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CHI3L1-IN-3

CAT: 0013-GTR19264252-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19264252-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CHI3L1-IN-3 is a CHI3L1 inhibitor that binds to CHI3L1 with dissociation constants (Kd) of 13.76 μM and 13.5 μM as measured by MST and SPR assays, respectively. It demonstrates an extended plasma half-life and microsomal stability, along with a low intrinsic clearance rate. In three-dimensional multicellular glioblastoma (GBM) spheroid models, CHI3L1-IN-3 induces dose-dependent cytotoxicity, reduces spheroid mass, and inhibits cell migration. This compound is valuable for glioblastoma research.
Field of Research
Cell Biology, Metabolism Research
Storage Conditions
-20°C
Notes
For research use only.

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