Products for Research Use Only
RegisterLogin

SR-2890

CAT: 0013-GTR19258826-02Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19258826-02Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SR-2890 is a potent and highly selective casein kinase 1δ/1ε (CK1δ/ε) inhibitor with an IC50 of 4 nM for CK1δ. This compound inhibits melanoma A375 cell growth with an EC50 of 38 nM in MTT assays and possesses pharmacokinetic properties suitable for xenograft studies using human cancer cell lines.
CAS Number
1454584-91-8
Product Name Alternative
SR2890
Field of Research
Metabolism Research, Stem Cell & Developmental Biology
Purity
99.10% (May vary between batches)
Smiles
FC1=CC=CC (=C1) N2C=NC=3C (=NC (=NC32) N4CCNCC4) NCC5=NC=6C=CC (Cl) =CC6N5
Molecular Formula
C23H21ClFN9
Molecular Weight
477.93
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

N-[(6-chloro-1H-benzimidazol-2-yl)methyl]-9-(3-fluorophenyl)-2-piperazin-1-ylpurin-6-amine
CAS Number1454584-91-8
PubChem CID56947189
IUPAC NameN-[(6-chloro-1H-benzimidazol-2-yl)methyl]-9-(3-fluorophenyl)-2-piperazin-1-ylpurin-6-amine
Molecular FormulaC23H21ClFN9
Molecular Weight477.9
XLogP3.7
Topological Polar Surface Area99.6
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count8
Rotatable Bond Count5
Heavy Atom Count34
Formal Charge0
Complexity685
SMILES
C1CN(CCN1)C2=NC(=C3C(=N2)N(C=N3)C4=CC(=CC=C4)F)NCC5=NC6=C(N5)C=C(C=C6)Cl
InChI
InChI=1S/C23H21ClFN9/c24-14-4-5-17-18(10-14)30-19(29-17)12-27-21-20-22(32-23(31-21)33-8-6-26-7-9-33)34(13-28-20)16-3-1-2-15(25)11-16/h1-5,10-11,13,26H,6-9,12H2,(H,29,30)(H,27,31,32)
InChIKey
NGIQKILKGCPSJO-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-[(6-chloro-1H-benzimidazol-2-yl)methyl]-9-(3-fluorophenyl)-2-piperazin-1-ylpurin-6-amine
CAS: 1454584-91-8
CID: 56947189
Formula: C23H21ClFN9
MW: 477.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight477.9
XLogP33.7
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count8
Rotatable Bond Count5
Exact Mass477.1592476
Monoisotopic Mass477.1592476
Topological Polar Surface Area99.6 Ų
Heavy Atom Count34
Formal Charge0
Complexity685
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19208984-01SR 27417A
GTR19208982-01SR 27388
GTR19200808SR 140333
GTR19200805-01SR 16584
GTR19199611-01SR-4326
GTR19199113SR 43845
GTR19196438-01SR 271425
GTR19190612-01SR 12460
GTR19203071-01SR-31747
GTR19202435-01SR 2595

Alternative Products

CatalogName
T206044-01SR-2890
TL312618VGRIA1 Human shRNA Lentiviral Particle (Locus ID 2890)
TR312618GRIA1 Human shRNA Plasmid Kit (Locus ID 2890)
SR301942GRIA1 Human siRNA Oligo Duplex (Locus ID 2890)
MBS131538SR-3029 (SR 3029; SR3029)
AR-N01202-01Nebivolol Impurity 11 (SR, SR)
BA4715-5.1SR-0813
BA3582-10SR-18292
B5591-50SR 16584
B5510-50SR 140333

Popular Products