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SR 12460

CAT: 0013-GTR19190612-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19190612-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SR 12460 is a small molecule that acts as an NBD mimetic, disrupting the IKKβ/NEMO interaction to inhibit NF-κB activation triggered by TNF-α or LPS. It has demonstrated efficacy in cellular assays and reduces acute pulmonary inflammation in mouse models, making it a useful research tool for studying inflammatory signaling pathways.
CAS Number
2055101-66-9
Smiles
O=C (NC1=NC=C (Cl) C=C1) CNCCC=2C=C (F) C=C (F) C2
Molecular Formula
C15H14ClF2N3O
Molecular Weight
325.74
Storage Conditions
-20°C
Notes
For research use only.

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