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TGFβRI-IN-7

CAT: 0013-GTR19258226-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19258226-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TGFβRI-IN-7 (compound 16W) is a potent inhibitor of TGFβRI. It effectively inhibits the phosphorylation of SMAD2/3 and reduces the viability of H22 cells, with IC50 values of 12 nM and 65 nM, respectively. In an H22 cell xenograft model, TGFβRI-IN-7 exhibits antitumor efficacy with a TGI of 79.6%.
Field of Research
Stem Cell & Developmental Biology
Smiles
CN (C) CCN1C=C (C=N1) C2=CC3=NC=CC (=C3C=C2) OC4=CN (N=C4C5CCOCC5) C6CC6
Molecular Formula
C27H32N6O2
Molecular Weight
472.582
Storage Conditions
-20°C
Notes
For research use only.

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