Products for Research Use Only

ERK2-IN-6

CAT: 0013-GTR19257889-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19257889-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ERK2-IN-6 (Compound 20) is a highly selective ERK1/2 inhibitor with an IC50 value of 7.9 nM for ERK2. It effectively inhibits the proliferation of BRAFV600E mutant cells, with an IC50 of 250 nM in A375 cells. ERK2-IN-6 shows potential for research in solid tumors such as melanoma with BRAF mutations.
CAS Number
2095713-33-8
Field of Research
Cell Biology, Signal Transduction
Smiles
O=C1C=2C=C (C=CC2CN1CC (=O) NC (C=3C=CC=CC3) (C) C) C4=NC (=NC=C4Cl) NC5CCOCC5
Molecular Formula
C28H30ClN5O3
Molecular Weight
520.02
Storage Conditions
-20°C
Notes
For research use only.