Products for Research Use Only

FGFR-IN-18

CAT: 0013-GTR19257567-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19257567-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FGFR-IN-18 (Compound KF7) is a covalent inhibitor targeting lysine on FGFR, exhibiting IC50 values of 1.1 nM for FGFR2, 1.3 nM for FGFR1, and 31.5 nM for FGFR4. It also shows affinity for FGFR3, with an inhibition rate of 52% at 10 nM. FGFR-IN-18 covalently modifies Lys485, a reactive site on FGFR.
Field of Research
Cardiovascular Research, Signal Transduction
Molecular Formula
C32H37N9O6
Storage Conditions
-20°C
Notes
For research use only.