Products for Research Use Only

RIP1-IN-1

CAT: 0013-GTR19258644-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19258644-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RIP1-IN-1 is an orally bioavailable RIP1 inhibitor with a high binding affinity (Kd: 110 nM) . This compound exhibits significant activity against necroptosis and effectively suppresses necrosome formation by inhibiting the phosphorylation of RIP1, RIP3, and MLKL pathways. RIP1-IN-1 can inhibit necroptosis and is applicable in research on acute liver injury.
Field of Research
Cell Biology, Signal Transduction
Storage Conditions
-20°C
Notes
For research use only.