SHMT-IN-4

CAT: 0804-HY-162883Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-162883Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SHMT-IN-4 (Compound 9ay) is a herbicide that targets and inhibits serine hydroxymethyltransferase (SHMT1) with an IC50 value of 193.8 g a.i./ha (active ingredient content per hectare) . SHMT-IN-4 interferes with amino acid synthesis and metabolism in plants by binding to SHMT1, thereby inhibiting plant growth. Additionally, SHMT-IN-4 shows no significant toxicity to maize and honeybees[1].
CAS Number
[3014814-72-0]
UNSPSC
12352101
Target
SHMT
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/shmt-in-4.html
Smiles
O=C(OC)C1=CC(NC(CN2CCN(C(COC3=CC=C(Br)C=C3Cl)=O)CC2)=O)=C(C(OC)=O)C=C1
Molecular Formula
C24H25BrClN3O7
Molecular Weight
582.83
References & Citations
[1]Luo D, et al. A first-in-class dimethyl 2-acetamido terephthalate inhibitor targeting Conyza canadensis SHMT1 with a novel herbicidal mode-of-action. J Adv Res. 2024 Aug;62:59-70.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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