Products for Research Use Only

SHMT-IN-3

CAT: 0013-GTR19241229-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19241229-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SHMT-IN-3 (Hit 1) is a potent, non-competitive serine hydroxymethyltransferase (SHMT) inhibitor, demonstrating an IC50 of 0.53 μM against human SHMT1. This compound is a valuable chemical probe for investigating one-carbon metabolism in cancer research, applicable in both cellular and biochemical in vitro studies.
CAS Number
330638-43-2
Smiles
O=C (O) CCC (=O) NC=1C=CC (=CC1) C2=NC=CC (=N2) C=3C=CC (=CC3) NC (=O) CCC (=O) O
Molecular Formula
C24H22N4O6
Molecular Weight
462.46
Storage Conditions
-20°C
Notes
For research use only.