CDK4/6-IN-23

CAT: 0013-GTR19250114-01Size: 50 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19250114-01Size:50 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

CDK4/6-IN-23 (Compound 42) is a potent, selective CDK4/6 inhibitor with an IC50 of 11 nM against CDK6. It exhibits immunomodulatory activity by activating immune cells and increasing IL-3 production. In vivo studies in 5-FU-treated mice show it provides bone marrow protection alongside its immunoenhancing effects.

Field of Research

Cell Biology, Signal Transduction

Smiles

CC (=O) N1CCC2 (CC1) CC (=O) C3=C (O2) C=C (C=C3) C4=NC (=NC=C4F) NC5=NC=C (C=C5) N6CCN (CC6) C (=O) C7CC7

Molecular Formula

C32H34FN7O4

Molecular Weight

599.655

Storage Conditions

-20°C

Notes

For research use only.

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CDK4/6-IN-23

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