CDK4/6-IN-3

CAT: 0013-GTR19206281-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19206281-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

CDK4/6-IN-3 is a brain-penetrant small molecule with potent, selective inhibition of CDK4 (Ki <0.3 nM) and CDK6 (Ki 2.2 nM) and weaker activity against CDK1 (Ki 110 nM) . It is utilized in preclinical glioblastoma research for investigating CDK4/6 signaling in both in vitro and in vivo models.

CAS Number

2366237-37-6

Field of Research

Cell Biology, Signal Transduction

Smiles

C (C) N1CC2 (CN (C2) C=3C=CC (NC=4N=C (C (F) =CN4) C5=C6N (N=C5) CCCC[C@H]6C) =NC3) C1

Molecular Formula

C25H31FN8

Molecular Weight

462.57

Storage Conditions

-20°C

Notes

For research use only.

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CDK4/6-IN-3

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