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Mc-Pro-PAB-MMAE

CAT: 0013-GTR19249912Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19249912Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mc-Pro-PAB-MMAE is a small molecule drug-linker conjugate designed for ADC synthesis, comprising the potent cytotoxin monomethyl auristatin E (MMAE) and a protease-cleavable linker. It is widely used in research for constructing ADCs to evaluate their efficacy and mechanism in both in vitro cytotoxicity assays and in vivo xenograft models.
CAS Number
2766450-03-5
Smiles
[C@H] ([C@H] (C (N[C@@H] ([C@@H] (O) C1=CC=CC=C1) C) =O) C) (OC) [C@]2 (N (C (C[C@H] ([C@@H] (N (C ([C@@H] (NC ([C@@H] (N (C (OCC3=CC=C (NC (=O) [C@H]4N (C (CNC (CCCCCN5C (=O) C=CC5=O) =O) =O) CCC4) C=C3) =O) C) [C@@H] (C) C) =O) C (C) C) =O) C) [C@H] (CC) C) OC) =O) CCC2) [H]
Molecular Formula
C64H95N9O14
Molecular Weight
1214.49
Storage Conditions
-20°C
Notes
For research use only.

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