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EGFR-IN-144

CAT: 0013-GTR19250063-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19250063-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EGFR-IN-144 is a dual-action small molecule inhibitor targeting both EGFR and tubulin polymerization, demonstrating potent nanomolar cytotoxicity. It induces G1/S phase arrest and apoptosis in cancer cells while downregulating key signaling proteins like mTOR and pro-inflammatory cytokines, supporting its application in oncology research for in vitro mechanistic studies.
Field of Research
Cardiovascular Research, Cell Biology, Immunology & Inflammation, Signal Transduction
Smiles
CC1=C (N=NN1C2=C (C=C (C=C2) Cl) Cl) C (=O) /C=C/C3=CC (=C (C=C3) OC) OC
Molecular Formula
C20H17Cl2N3O3
Molecular Weight
418.273
Storage Conditions
-20°C
Notes
For research use only.

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