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FMP

CAT: 0013-GTR19249322-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19249322-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FMP, a platinum (IV) complex, demonstrates potent antiproliferative activity against breast cancer cells. It induces DNA damage (γ-H2AX upregulation), oxidative stress (ROS increase), and activates both extrinsic and intrinsic apoptotic pathways, as evidenced by elevated p53, DR5, caspase-8, Cyt-c, and cleaved-PARP1. This mechanism supports its investigation in preclinical oncology research.
Field of Research
Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Metabolism Research, Molecular Biology, Protein Biochemistry, Signal Transduction
Molecular Formula
C18H18Cl2N2O7Pt
Molecular Weight
640.33
Storage Conditions
-20°C
Notes
For research use only.

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