Isoxsuprine hydrochloride
CAT:
804-HY-B1270-02
Size:
200 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Isoxsuprine hydrochloride
- CAS Number: 579-56-6
- UNSPSC Description: Isoxsuprine hydrochloride is a beta-adrenergic receptor agonist with Kis of 13.65 μΜ and 3.48 μΜ for myometrial and placcntal beta-adrenergic receptor, respectively. Isoxsuprine hydrochloride is also a NMDA receptor antagonist.
- Target Antigen: Adrenergic Receptor; iGluR
- Type: Reference compound
- Related Pathways: GPCR/G Protein;Membrane Transporter/Ion Channel;Neuronal Signaling
- Applications: Neuroscience-Neurodegeneration
- Field of Research: Neurological Disease; Endocrinology
- Assay Protocol: https://www.medchemexpress.com/Isoxsuprine_hydrochloride.html
- Purity: 99.87
- Solubility: DMSO : 140 mg/mL (ultrasonic)|H2O : 15.56 mg/mL (ultrasonic)
- Smiles: OC(C(NC(C)COC1=CC=CC=C1)C)C2=CC=C(O)C=C2.[H]Cl
- Molecular Weight: 337.847
- References & Citations: [1]Falkay G, et al. Affinity of tocolytic agents on human placental and myometrial beta-adrenergic receptors. J Perinat Med. 1986;14(2):109-13.|[2]Kretschy N, et al. In vitro inhibition of breast cancer spheroid-induced lymphendothelial defects resembling intravasation into the lymphatic vasculature by acetohexamide, isoxsuprine, nifedipin and proadifen. Br J Cancer. 2013 Feb 19;108(3):570-8.|[3]Hill JW, et al. Identification of isoxsuprine hydrochloride as a neuroprotectant in ischemic stroke through cell-based high-throughput screening. PLoS One. 2014 May 7;9(5):e96761.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
- Clinical Information: Launched