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PF-4942847

CAT: 0013-GTR19241606-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19241606-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PF-4942847 is a novel, orally bioavailable Hsp90 inhibitor under investigation for triple-negative breast cancer (TNBC) due to its synergistic disruption of multiple oncogenic pathways. Its mechanism, demonstrated in vitro and in vivo, includes inducing AKT degradation in peripheral blood lymphocytes, a potential pharmacodynamic biomarker for clinical trials.
CAS Number
1046859-34-0
Smiles
O=C (NCC (F) (F) F) N1CC=2N=C (N=C (C=3C (Cl) =CC (Cl) =CC3OCCN4N=CC=C4) C2C1) N
Molecular Formula
C20H18Cl2F3N7O2
Molecular Weight
516.3
Storage Conditions
-20°C
Notes
For research use only.

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