Products for Research Use Only

SHMT-IN-2

CAT: 0013-GTR19186200-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19186200-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SHMT-IN-2 is a potent dual inhibitor of human serine hydroxymethyltransferase isoforms 1 and 2 (SHMT1/2) . It demonstrates potent anti-proliferative activity against various human cancer cell lines in vitro, with particular sensitivity noted in B-cell lymphoma models, making it a valuable chemical probe for oncology research.
CAS Number
2102681-49-0
Product Name Alternative
SHMT1, SHMT2
Purity
98.45% (May vary between batches)
Solubility
DMSO:90 mg/mL (208.6 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.65 mM)
Smiles
CC (C) C1 (c2c (C) n[nH]c2OC (N) =C1C#N) c1cc (cc (c1) C (F) (F) F) N1CCCC1
Molecular Formula
C22H24F3N5O
Molecular Weight
431.45
Storage Conditions
-20°C
Notes
For research use only.