Products for Research Use Only

Pan-TEAD-IN-1

CAT: 0013-GTR19241143-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19241143-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pan-TEAD-IN-1 is a potent, orally bioavailable pan-TEAD inhibitor that blocks YAP/TAZ coactivator binding by targeting TEAD palmitoylation. It effectively suppresses downstream oncogenes (e.g., Ctgf, Cyr61) in vitro and demonstrates significant anti-tumor activity in TEAD-dependent cancer xenograft models, making it a valuable research tool for Hippo pathway and oncology studies.
CAS Number
3027484-09-6
Field of Research
Stem Cell & Developmental Biology
Smiles
O=C (C=C) N1CC=2C=C (C=CC2CC1) C3=CC=C (C=C3) C (F) (F) F
Molecular Formula
C19H16F3NO
Molecular Weight
331.33
Storage Conditions
-20°C
Notes
For research use only.