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JAK/HDAC-IN-4

CAT: 0013-GTR19239551-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19239551-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JAK/HDAC-IN-4 (compound 11i) is a potent dual JAK2/HDAC6 inhibitor with IC50 values of 0.49 nM and 12 nM, respectively. It demonstrates anti-proliferative activity, suppresses nitric oxide production in vitro, and effectively reduces psoriasiform lesions in an imiquimod-induced mouse model with a favorable toxicity profile.
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Molecular Biology, Signal Transduction, Stem Cell & Developmental Biology
Molecular Formula
C30H32N8O5S
Molecular Weight
616.69
Storage Conditions
-20°C
Notes
For research use only.

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