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Thalidomide-N-methylpiperazine

CAT: 0013-GTR19239076-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19239076-01Size:50 mg
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Description
Thalidomide-N-methylpiperazine serves as an E3 ligase ligand-linker conjugate for constructing PROTAC MLKL Degrader-2. This molecule exhibits antinecroptotic function in human cell lines and has been shown to degrade MLKL in the HT-29 xenograft mouse model, supporting research in targeted protein degradation and necroptosis.
CAS Number
2924858-30-8
Field of Research
Pharmacology & Drug Discovery
Smiles
O=C1NC (=O) C (N2C (=O) C3=CC=C (C=C3C2=O) N4CCN (C) CC4) CC1
Molecular Formula
C18H20N4O4
Molecular Weight
356.38
Storage Conditions
-20°C
Notes
For research use only.

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