Products for Research Use Only

ONO-7579

CAT: 0013-GTR19239064-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19239064-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ONO-7579 is a potent and orally bioavailable TRKA inhibitor that suppresses tumor growth by blocking TRKA phosphorylation. It demonstrates in vivo efficacy, with an EC50 of 17.6 ng/g in KM12 colorectal cancer xenograft models, making it a valuable tool for investigating TRKA-driven cancers in preclinical research.
CAS Number
1622212-25-2
Field of Research
Signal Transduction
Smiles
O=C (NC1=CN=C (N=C1) OC=2C=CC (=CC2) C3=CC (Cl) =CN=C3N) NC4=CC (=CC=C4S (=O) (=O) C) C (F) (F) F
Molecular Formula
C24H18ClF3N6O4S
Molecular Weight
578.95
Storage Conditions
-20°C
Notes
For research use only.