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PARP1-IN-31

CAT: 0013-GTR19238912-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19238912-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PARP1-IN-31 (compound 11f) is a potent PARP1 inhibitor (IC50 = 97 nM) suitable for lung adenocarcinoma research. It demonstrates anti-proliferative and pro-apoptotic effects in vitro, such as in A549 cells, by upregulating caspase-3/9. Its application extends to studying DNA damage response and potential combination therapies in cancer models.
CAS Number
684234-60-4
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology, Protein Biochemistry
Purity
98.99% (May vary between batches)
Solubility
DMSO:100 mg/mL (245.2 mM)
Smiles
O=C (NC1=CC=C (F) C=C1) CN2N=C (C=3C=CC (Cl) =CC3) C=4C=CC=CC4C2=O
Molecular Formula
C22H15ClFN3O2
Molecular Weight
407.83
Storage Conditions
-20°C
Notes
For research use only.

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