Products for Research Use Only

SH-E4A-66

CAT: 0013-GTR19238186-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19238186-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SH-E4A-66 is a covalent protein ligator (C2-COUPLr) built on a carbazole scaffold, utilizing a non-acrylamide/chloroacetamide cysteine-targeting warhead. It binds to and inhibits EML4-ALK kinase activity with EC50 and IC50 values of 1.5 μM and 2.3 μM, respectively, serving as a research tool for studying ALK-driven cancers in cellular models.
Field of Research
Cardiovascular Research, Signal Transduction
Storage Conditions
-20°C
Notes
For research use only.