Products for Research Use Only

KRASG12C IN-12

CAT: 0013-GTR19238158-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19238158-01Size:25 mg
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Description
IN-12 (compound-1) is a selective KRASG12C inhibitor that functions by forming a ternary complex with cyclophilin A (CYPA) and the activated KRASG12C mutant. This mechanism supports its use in vitro and in vivo for investigating targeted oncology and signal transduction in cancers driven by this mutation.
CAS Number
2093328-45-9
Field of Research
Signal Transduction
Smiles
[C@@H] (C (=O) N1N[C@H] (C (OC) =O) CCC1) (CC2=CC (O) =CC=C2) NC ([C@@H] (NC (CCCSSC3=CC=CC=N3) =O) [C@@H] (C) C) =O
Molecular Formula
C29H39N5O6S2
Molecular Weight
617.78
Storage Conditions
-20°C
Notes
For research use only.