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TAS-121

CAT: 0013-GTR19237744-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19237744-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TAS-121 is a potent, covalent third-generation EGFR-TKI that selectively targets mutant EGFR forms, including T790M resistance mutations, and inhibits HER2/4. It demonstrates robust antitumor efficacy in cellular assays and in vivo xenograft models, such as NCI-H1975, by blocking EGFR phosphorylation and downstream signaling.
CAS Number
1451370-01-6
Smiles
NC1=C2C (=C3N (C2=NC=N1) C[C@@H] (NC (C=C) =O) CC3) C4=CC5=C (N=C4) C=CC=C5
Molecular Formula
C22H20N6O
Molecular Weight
384.43
Storage Conditions
-20°C
Notes
For research use only.

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