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Pan-RAS-IN-6

CAT: 0013-GTR19238146-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19238146-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pan-RAS-IN-6 is a potent and selective DUSP6 inhibitor that suppresses MAPK signaling, demonstrating significant tumor growth inhibition and regression in NSCLC brain metastasis models. It exhibits high potency against key KRAS mutants (G12C, G12D, G12V) with low nanomolar IC50 values, making it a valuable tool for investigating KRAS-driven cancers in both in vitro and in vivo studies.
Field of Research
Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Molecular Formula
C46H60N8O5S
Molecular Weight
837.08
Storage Conditions
-20°C
Notes
For research use only.

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