Products for Research Use Only

PF-05661014

CAT: 0013-GTR19237780-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19237780-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PF-05661014 is a demethylated analog of PF-06526290 that selectively blocks Nav1.3 and Nav1.7 sodium channels by binding to the voltage-sensing domain (VSD) of domain 4 to stabilize their inactivated state. It is a research tool used in vitro and in vivo for studying pain pathways and sodium channel pharmacology.
CAS Number
2153474-85-0
Field of Research
Pharmacology & Drug Discovery
Smiles
O=C (NC1=CC=C (C=C1) S (=O) (=O) NC2=NC=CS2) NCC=3C=CC=CC3
Molecular Formula
C17H16N4O3S2
Molecular Weight
388.46
Storage Conditions
-20°C
Notes
For research use only.