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LSN3074753

CAT: 0013-GTR19237558-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19237558-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LSN3074753 is a pan-RAF and RAF dimer inhibitor that suppresses MAPK pathway activation in tumors driven by BRAF monomers or RAF dimers, such as colorectal cancers with BRAF or KRAS mutations. It shows additive/synergistic effects with Cetuximab in colorectal cancer PDX models, supporting its research use in both in vitro and in vivo oncology studies.
CAS Number
1455031-68-1
Field of Research
Signal Transduction
Smiles
CC=1C (=CC2=C (N1) C=C (NC) N=C2) C3=CC (NC (NC[C@H] (C (C) (C) C) O) =O) =C (F) C=C3C
Molecular Formula
C24H30FN5O2
Molecular Weight
439.53
Storage Conditions
-20°C
Notes
For research use only.

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CatalogName
HY-164492LSN3074753

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