Hydroxy-PEG10-Boc

• UNSPSC Description:

  Hydroxy-PEG10-Boc is extacted from patent CN108707228 (example 0024)[1]. Hydroxy-PEG10-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG10-Boc can be conjugated to Paclitaxel (HY-B0015) or docetaxel (HY-B0011)[2].

• Target Antigen:

  ADC Linker

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/hydroxy-peg10-boc.html

• Purity:

  98.0

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(OC(C)(C)C)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

• Molecular Weight:

  586.71

• References & Citations:

  [1]Huli, et al. A kind of preparation method of hydroxyl polyethylene glycol propionic ester. Patent CN108707228A.|[2]Miller ML, et al. Synthesis of taxoids with improved cytotoxicity and solubility for use in tumor-specific delivery.J Med Chem. 2004 Sep 23;47(20):4802-5.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  778596-26-2