Hydroxy-PEG10-Boc

• Description :

  Hydroxy-PEG10-Boc is extacted from patent CN108707228 (example 0024) [1]. Hydroxy-PEG10-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Hydroxy-PEG10-Boc can be conjugated to Paclitaxel (HY-B0015) or docetaxel (HY-B0011) [2].

• UNSPSC :

  12352203

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  ADC Linker

• Type :

  ADC Related

• Related Pathways :

  Antibody-drug Conjugate/ADC Related

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/hydroxy-peg10-boc.html

• Purity :

  99.86

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(OC(C)(C)C)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

• Molecular Formula :

  C27H54O13

• Molecular Weight :

  586.71

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Huli, et al. A kind of preparation method of hydroxyl polyethylene glycol propionic ester. Patent CN108707228A.|[2]Miller ML, et al. Synthesis of taxoids with improved cytotoxicity and solubility for use in tumor-specific delivery.J Med Chem. 2004 Sep 23;47 (20) :4802-5.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  ADC Related

• Clinical Information :

  No Development Reported

• CAS Number :

  [778596-26-2]