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CCR1 antagonist 12

CAT: 0013-GTR19236465-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19236465-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CCR1 antagonist12 (Compound 12) is a potent small molecule antagonist of human CCR1 (IC50 = 3 nM), effectively inhibiting CCL3-induced chemotaxis (IC50 = 9 nM) . It displays favorable pharmacokinetics in rats, making it a valuable tool for in vitro and in vivo research into inflammatory and autoimmune diseases mediated by CCR1 signaling.
CAS Number
921208-19-7
Field of Research
Immunology & Inflammation, Immunology & Inflammation; Pharmacology & Drug Discovery, Infectious Disease & Virology, Pharmacology & Drug Discovery
Smiles
O=C (C=CC1=CC (OC) =C (Cl) C=C1NC (=O) C) N2CC3N (CC4=CC=C (F) C=C4) C (COC3) C2
Molecular Formula
C25H27ClFN3O4
Molecular Weight
487.95
Storage Conditions
-20°C
Notes
For research use only.

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