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(R) -Vorbipiprant

CAT: 0013-GTR19236331-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19236331-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(R) -Vorbipiprant is a potent and selective EP4 receptor antagonist (Ki=16.6 nM) that inhibits PGE2-induced cAMP production (IC50=22 nM) . This orally active small molecule has demonstrated immunomodulatory and antiangiogenic effects in research, including efficacy in a murine collagen-induced arthritis model.
CAS Number
2502965-92-4
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Smiles
N (C (=O) [C@@H]1N (CC2=CC=C (C (F) (F) F) C=C2) CCC3 (C1) CC3) C4 (CC4) C5=CC=C (C (O) =O) C=C5
Molecular Formula
C26H27F3N2O3
Molecular Weight
472.5
Storage Conditions
-20°C
Notes
For research use only.

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HY-156649-01Vorbipiprant
T88706-01(R) -Vorbipiprant

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