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CDK8-IN-15

CAT: 0013-GTR19236265-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19236265-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CDK8-IN-15 (Compound 46) is a potent and selective CDK8 inhibitor (IC50 = 57 nM) that stabilizes the kinase and suppresses NF-κB signaling. It demonstrates anti-inflammatory activity in vitro by counteracting TNF-α-induced psoriatic responses and upregulating Foxp3 and IL-10, supporting its use in psoriasis and inflammatory disease research.
CAS Number
2988020-03-5
Field of Research
Cell Biology
Smiles
O=C (NC=1C=CC (=C (OC) C1) C2=CN=C3NC=CC3=C2) N4CCOCC4
Molecular Formula
C19H20N4O3
Molecular Weight
352.39
Storage Conditions
-20°C
Notes
For research use only.

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