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EGFR-IN-117

CAT: 0013-GTR19236256-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19236256-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EGFR-IN-117 (Compound 8h) is a potent and selective EGFR inhibitor effective against multiple resistant mutations, including L858R/T790M/C797S. It demonstrates nanomolar IC50 values in cell lines like H1975 and PC-9 and has shown in vivo anti-tumor efficacy in mouse models, supporting its use in oncology research targeting EGFR-driven cancers.
CAS Number
3035639-05-2
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
O=S (=O) (NC=1C=CC=CC1NC2=NC (=NC=C2Br) NC3=CC=C (C=C3) N4CCN (C) CCC4) C5CC5
Molecular Formula
C25H30BrN7O2S
Molecular Weight
572.52
Storage Conditions
-20°C
Notes
For research use only.

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